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Email: ggci@yale.edu

Hosted by the Yale Center for Green Chemistry and Green Engineering

Designed by Seon Augusto Ferreira

5-Day Train the Facilitator Workshop

Workshop Agenda

A five day agenda with learning objectives and topics to be covered by lectures, exercises and case studies during TTF. Document downloadable in a PDF or DOCX format. 

DAY 1
Introduction presentation
  1. Sustainability – Myths and Facts

  2. Society, Economy, and the Environment

  3. Business and Sustainability

  4. Applying Green Chemistry to Management

Sustainability I, II, III 

5. Different Models of Sustainability

6. Case Study: The Interface Company 

7. Processes for Reporting and Measuring Sustainable Actions

8. Life Cycle Assessment - Definitions & Examples

Disasters, Accidents and Unintended Consequences 
  1. Chemical and Industrial Accidents

  2. Unintended Consequences

  3. Green Chemistry is Everybody's Job

  4. Perspective and Context

  5. Green Chemistry — Where do we go from here?

Life Cycle - Input Output - Class Exercise
DAY 2
Definition & Benefits of Green Chemistry
  1. Green Chemistry and Design Criteria

  2. Chemical Design
    A. Current Innovations in Chemical Design​

  3. Green Chemistry Design in Other Fields

4.​ The Market for Green Chemistry

5. Green Chemistry Benefits are In Demand

6. Applications of Green Chemistry - Examples

The 12 Principles of Green Chemistry I, II
  1. The Twelve Principles of Green Chemistry

  2. Industrial Examples of Green Chemistry

Renewable Feedstocks
  1. Energy and Feedstock Consumption

  2. Petroleum

  3. Renewable Feedstocks

4. Renewable Feedstocks as a Source of Energy

5. First, Second, and Third Generation Feedstocks

6. The Advantages and Drawbacks of Biofuel

Using the 12 Principles - Class Exercise
DAY 3
Catalysis
  1. Activation Energy for Reaction

  2. What is a Catalyst?

  3. Types of Catalysts

  4. Catalysts and Sustainability

  5. Important Improvements Using catalysts

  6. Enzymatic Reactions

  7. Examples and Considerations

Solvents
  1. What are solvents and how are they used?

  2. Conventional Solvents

  3. Alternative Solvents

  4. Solvent Selection

  5. In-Class Exercise

  6. Solvent Replacement

Waste Prevention
  1. The Waste Treatment Pyramid

  2. Reduced Solvent Use

  3. Waste as a Feedstock

  4. Biodegradation of Waste

  5. Designing Processes to Include Biodegradation of Waste

  6. In-Class Exercise

Metrics
  1. Why do We Need Metrics in Green Chemistry?

  2. Established Metrics in Green Chemistry

  3. Additional Metrics Used in Green Chemistry

  4. In-Class Discussion

Solvents - Class Exercise
Biodegradation - Class Exercise
Team 1 additional file
Team 2 additional file
Team 3 additional file
Team 4 additional file
DAY 4
Design for Reduced Hazard I, II
  1. Hazard and Risk — Past and Present

  2. Toxicology

  3. In-Class Discussion

  4. Asserting Hazards and Exposure
    a. What Happens When You're Exposed?

5. In-Class Exercise

6. Hazard Minimization Through Molecular Design

7. QSAR — Quantitative Structure Activity Relationship

Molecular Design research Network (MoDRN)

From Theory to Practice
  1. Implementation: Why, What, and How

  2. Understanding Context
    a. Green Chemistry in the Marketplace

  3. Identifying Opportunities
    a. Life Cycle and Green Chemistry Principles as a Guide to Finding Opportuinities

4. Delivering Innovation

5. Green Chemistry Strategies at All Stages

        a. Green Chemistry Assessment Tool

6. How to Proceed: Moving Forward

Innovation
  1. Transformative Innovation

  2. Nature as Inspiration

  3. Design Challenges
    a. Color

  4. There is Still More We Can Learn From Nature

ADME — Class Exercise
ADDITIONAL DOCUMENTS
Tools
MedChem Tips and Tricks on Purification
ACS GCI Pharmaceutical Roundtable Solvent Selection Guide
Design Principles for Sustainable Green Chemistry and Engineering
List of Resources for Hazard and Toxicological Screening and Research
Reagent Guides by ACS Pharmaceutical Roundtable
Process Mass Intensity Calculator
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